Specifications
Immunogen
Fusion protein containing internal amino acids 194 - 272 of Human ABCC10.
Applications
Application Notes
ICC : 1/20 - 1/50; IHC-Fr: 1/20; WB: 1/20 - 1/50;
Target
Alternative Names
ABCC10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; multidrug resistance-associated protein 7; ABCC10; ATP binding cassette, sub family C (CFTR/MRP), member 10; ATP binding cassette, subfamily C, member 10; ATP-binding cassette sub-family C
Product Background
Antigen Description
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;
Citations
Publication ()
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