Full length protein corresponding to amino acids 1-242 of Human TIP30 (NP_006401.2).
Conjugate
Unconjugated
Target
Alternative Names
HTATIP2; HIV-1 Tat interactive protein 2, 30kDa; CC3; TIP30; SDR44U1; oxidoreductase HTATIP2; Tat-interacting protein (30kD); HIV-1 TAT-interactive protein 2; 30 kDa HIV-1 TAT-interacting protein; short chain dehydrogenase/reductase family 44U, member 1;
Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
Citations
Publication ()
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