HSPA1B (NP_005336, 531 a.a. ~ 611 a.a) partial recombinant protein with GST tag. The sequence is VQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKD EFEHKRKELEQVCNPIISGLY
Conjugate
Unconjugated
Target
Alternative Names
HSPA1B; heat shock 70kDa protein 1B; HSP70-2; HSP70-1B; heat shock 70 kDa protein 1A/1B; HSP70-1/HSP70-2; HSP70.1/HSP70.2; heat shock 70kD protein 1B; heat shock 70 kDa protein 1/2;
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Pathway
AUF1 (hnRNP D0) destabilizes mRNA; Antigen processing and presentation; Attenuation phase; Cellular responses to stress
Citations
Publication ()
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