Specifications
Immunogen
Recombinant full length protein corresponding to Human HPRT aa 1-218.Sequence: MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLA RDVMKEMGGHH IVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVD FIRLKSYCNDQSTGDIKVIGGDD LSTLTGKNVLIVEDIIDTGKTMQTL LSLVRQYNPKMVKVASLLVKRTPRS
Applications
Application Notes
WB: 1/4000; ICC/IF: 1/100;
Target
Alternative Names
HPRT1; hypoxanthine phosphoribosyltransferase 1; HPRT; hypoxanthine-guanine phosphoribosyltransferase; HGPRT; Lesch Nyhan syndrome; HGPRTase;
Product Background
Antigen Description
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
Pathway
Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Nucleotide Metabolism, organism-specific biosystem; Purine metabolism, organism-specific biosystem;
Citations
Publication ()
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COA
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