Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Pathway
Arachidonic acid metabolism; Metabolism of lipids and lipoproteins; Synthesis of Lipoxins (LX); Transcriptional misregulation in cancer
Citations
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