Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human hnRNP U aa 750 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: Q00839
Applications
Application Notes
WB: 1/1000 - 1/5000; IHC-P: 1/50 - 1/100; ICC/IF: 1/250 - 1/500;
Target
Alternative Names
HNRNPU; heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); HNRPU; heterogeneous nuclear ribonucleoprotein U; hnRNPU; SAF A; pp120; p120 nuclear protein; scaffold attachment factor A; SAF-A; U21.1; hnRNP U;
Product Background
Antigen Description
Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA.
Pathway
Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem;
Citations
Publication ()
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