Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (ENLMTSSTLP PLFADEDGSK ESNDLATTGL NHPEVPYSSG ATSSTNNPEF) of human HMG20A (NP_060670).
Conjugate
Unconjugated
Applications
Application Notes
ELISA titre using peptide based assay, 1:1562500. WB: Use at a concentration of 1 ug/ml. Predicted molecular weight: 40 kDa. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Target
Alternative Names
HMG20A; high mobility group 20A; high mobility group protein 20A; FLJ10739; HMG box domain containing 1; HMGX1; HMGXB1; high-mobility group 20A; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1;
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4.
Citations
Publication ()
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