Specifications
Immunogen
Recombinant full length protein corresponding to Human HMBS aa 1-361. produced in HEK293T cell.Sequence: MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQ FEIIAMSTTGDKILDTALSK IGEKSLFTKELEHALEKNEVDLVVHSLK DLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEK SVVGTS
Applications
Application Notes
WB: 1/2000;
Target
Alternative Names
HMBS; hydroxymethylbilane synthase; PBGD, PORC, porphobilinogen deaminase , porphyria, acute; Chester type , UPS, uroporphyrinogen I synthase; porphobilinogen deaminase; uroporphyrinogen I synthase; pre-uroporphyrinogen synthase; uroporphyrinogen I syn
Product Background
Antigen Description
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Pathway
Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; Porphyrin and chlorophyll metabolism, conserved biosystem;
Citations
Publication ()
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