Mouse anti-Human HLTF polyclonal antibody

Species Reactivity

Human

Immunogen

SMARCA3 (NP_003062, 932 a.a. ~ 1009 a.a) partial recombinant protein with GST tag. The sequence is PAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNKKRELAAGAFGTKKPN ADEMKQAKINEIRTLIDL

Conjugate

Alternative Names

HLTF; helicase-like transcription factor; ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3; SNF2-like 3; RING finger protein 80; sucrose nonfermenting-like 3; sucrose nonfermenting protein 2-like 3; DNA-binding protein/plasminogen activator inhibitor

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.

Pathway

RB in Cancer;