Anti-HIV type 2 Glycoprotein 39 Polyclonal antibody (DPAB4261)

Rabbit Anti-HIV type 2 Glycoprotein 39 Polyclonal antibody for ELISA

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
HIV
Immunogen
Recombinant HIV-2 protein
Conjugate
Unconjugated

Target


Alternative Names
HIV-2 Ag gp39; Human Immunodeficiency Virus Type 2 Antigen, envelope gp39; Human immunodeficiency virus; HIV; Gp39; HIV 2

Product Background


Antigen Description
Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells), macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosisin infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunityis lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Hayashi, T; Rao, SP; et al. Role of CD40 ligand in Mycobacterium avium infection. INFECTION AND IMMUNITY 67:3558-3565(1999).

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