Anti-HIST2H2AC monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human HIST2H2AC is used for rabbit immunization.

Conjugate

Alternative Names

HIST2H2AC; histone cluster 2, H2ac; H2A; H2A/q; H2AFQ; H2A-GL101; histone H2A type 2-C; histone IIa; histone H2A/q; histone 2, H2ac; histone H2A-GL101; H2A histone family, member Q;

Entrez Gene ID

UniProt ID

Antigen Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

Pathway

Alcoholism; Amyloids; Cell Cycle; Cell Cycle, Mitotic; Cellular Senescence; Cellular responses to stress; Chromatin modifying enzymes; Chromatin organization; Chromosome Maintenance; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence.