Anti-HIST1H2BA monoclonal antibody, clone FQS23992

Antibody Isotype

IgG

Clone

FQS23992

Species Reactivity

Mouse; Human

Immunogen

Recombinant fragment within Human Histone H2B (testis specific). The exact sequence is proprietary.Database link: Q96A08

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IHC-P: 1/100 - 1/250; IP: 1/10 - 1/100.

Alternative Names

HIST1H2BA; histone cluster 1, H2ba; H2B histone family, member U, (testis specific) , histone 1, H2ba; histone H2B type 1-A; bA317E16.3; H2BFU; STBP; TSH2B; histone 1, H2ba; histone H2B, testis; testis-specific histone H2B; H2B histone family, member U,

Entrez Gene ID

UniProt ID

Antigen Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.

Pathway

Amyloids, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Disease, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem.