Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human HIBADH aa 300 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P31937
Applications
Application Notes
WB: 1/10000 - 1/50000; IHC-P: 1/100 - 1/250; ICC/IF: 1/250 - 1/500; Flow Cyt: 1/10 - 1/100; IP: 1/100 - 1/500;
Target
Alternative Names
HIBADH; 3-hydroxyisobutyrate dehydrogenase; 3-hydroxyisobutyrate dehydrogenase, mitochondrial; NS5ATP1; MGC40361;
Product Background
Antigen Description
This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.
Pathway
Branched-chain amino acid catabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Valine, leucine and isoleucine degradation, organism-specific biosystem; Valine, leucine and isoleucine degradation, conserved biosystem;
Citations
Publication ()
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COA
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