KLH conjugated synthetic peptide derived from human HERV-FRD : 331-430/538
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-2000
General Notes
This product (Catalog No. DPABH-09147) is a rabbit-derived IgG polyclonal antibody raised against human ERVFRD-1, targeting the amino acid region 331–430 of the protein. It has been affinity purified by protein A. Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. DPABH-09147 is suitable for use in Western blot (WB) (1:500–1:2,000) application. DPABH-09147 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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