This product (Catalog No. DPABH-20309) is a rabbit-derived polyclonal antibody raised against human HENMT1. It has been affinity purified by Protein A. HENMT1 (HEN Methyltransferase 1) is an enzyme essential for stabilizing piRNAs (piwi-interacting RNAs) by adding a 2'-O-methyl group to their 3'-ends. Primarily acting in the germline, it is critical for suppressing transposable elements (TEs) to maintain genome integrity and fertility. HENMT1 also operates in somatic cells, restricting endogenous retrovirus (ERV) activity. DPABH-20309 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:30–1:150) applications. DPABH-20309 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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