Species Reactivity: Mouse, Human, Rat, Horse, Rabbit
Summary
Specifications
Antibody Isotype
IgG
Species Reactivity
Mouse; Human; Rat; Horse; Rabbit
Immunogen
KLH conjugated synthetic peptide derived from human Hyaluronan-binding protein 2 27 kDa light chain: 271-370/560
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-2000
General Notes
This product (Catalog No. DPABH-18170) is a rabbit-derived IgG polyclonal antibody raised against human HABP2, targeting the amino acid region 271–370 of the protein. This antibody exhibits cross-reactivity with HABP2 from mouse, rat, horse, and rabbit. It has been affinity purified by Protein A. This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. DPABH-18170 is suitable for use in Western blot (WB) (1:500–1:2,000) application. DPABH-18170 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Hyaluronan-binding protein 2 27 kDa light chain; Factor seven activating protease; Factor seven-activating protease; Factor VII activating protein; Factor VII-activating protease; FSAP; HABP 2; HABP; Habp2; HABP2_HUMAN; Hepatocyte growth factor activator like protein; Hepatocyte growth factor activator-like protein; HGFAL; Hyaluronan binding protein 2; Hyaluronic acid binding protein 2; PHBP; Plasma hyaluronan binding protein; Plasma hyaluronan-binding protein
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