Specifications
Species Reactivity
Mouse; Rat
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GCAP2 aa 150 to the C-terminus. The exact sequence is proprietary.Database link: Q9UMX6
Applications
Application Notes
WB: 1/1000 - 1/2000;
Target
Alternative Names
GUCA1B; guanylate cyclase activator 1B (retina); guanylyl cyclase-activating protein 2; GCAP2; GCAP 2; guanylate cyclase-activating protein, photoreceptor 2; RP48; GUCA2; DKFZp686E1183;
Product Background
Antigen Description
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Pathway
Olfactory transduction, organism-specific biosystem; Olfactory transduction, conserved biosystem; Phototransduction, organism-specific biosystem; Phototransduction, conserved biosystem; Visual signal transduction: Cones, organism-specific biosystem; Visual signal transduction: Rods, organism-specific biosystem.
Citations
Publication ()
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COA
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