GSTT2 (NP_000845, 145 a.a. ~ 244 a.a) partial recombinant protein with GST tag. The sequence is WLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAE LCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP
Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries.
Pathway
Biological oxidations; Chemical carcinogenesis; Drug metabolism - cytochrome P450; Glutathione metabolism
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