Specifications
Species Reactivity
Mouse; Rat; Chicken; Cow; Dog; Human
Immunogen
Full length native protein (purified) corresponding to Human GRK1.
Applications
Application Notes
ICC/IF: 1/100 - 1/200; WB: 1 μg/ml.
Target
Alternative Names
GRK1; G protein-coupled receptor kinase 1; rhodopsin kinase , RHOK; rhodopsin kinase; GPRK1; RK; RHOK;
Product Background
Antigen Description
Phosphorylates rhodopsin thereby initiating its deactivation. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
Pathway
Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Phototransduction, organism-specific biosystem; Phototransduction, conserved biosystem; Visual signal transduction: Cones, organism-specific biosystem.
Citations
Publication ()
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