Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Fusion protein (His-tag) corresponding to Rat NMDAR2A aa 75-325 (N terminal).Sequence: NRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSQTFIPI LGIHGGASMI MADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGYRDFI SFIKTTVDNS FVGWDMQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVL
Applications
Application Notes
WB: 1/1000;
Target
Alternative Names
GRIN2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor subunit 2A; NR2A; NMDAR2A;
Product Background
Antigen Description
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem;
Citations
Publication ()
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COA
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