General Notes
This product (Catalog No. DPABH-21256) is a rabbit-derived polyclonal antibody raised against human GPR19, targeting the amino acid region 315–415 of the protein. This antibody exhibits cross-reactivity with Human GPR19 from mouse. It has been affinity purified by Protein A. GPR19 (G protein-coupled receptor 19) is an orphan member of the class A rhodopsin-like GPCR family encoded in the human genome. It is a seven-transmembrane receptor predicted to couple to heterotrimeric G proteins, but its endogenous ligand has not been definitively established. GPR19 is expressed in multiple tissues, with notable expression in the brain and endocrine-related tissues, suggesting potential roles in neuroendocrine regulation and energy homeostasis. Some studies have implicated GPR19 in metabolic processes and circadian regulation, possibly linking it to pathways such as the circadian rhythm. Despite these associations, the precise signaling mechanisms, physiological functions, and therapeutic relevance of GPR19 remain incompletely understood and require further experimental validation.
DPABH-21256 is suitable for use in IHC (1:50–1:500) application.
DPABH-21256 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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