Anti-GPR18 monoclonal antibody, clone FQS23460

Antibody Isotype

IgG

Clone

FQS23460

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GPCR GPR18 aa 300 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: Q14330

Conjugate

Application Notes

WB: 1/1000 - 1/5000;

Alternative Names

GPR18; G protein-coupled receptor 18; N-arachidonyl glycine receptor; NAGly receptor; G-protein coupled receptor 18;

Entrez Gene ID

UniProt ID

Antigen Description

G protein coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR18 is a member of this family and has been reported to be expressed at high levels in testis and spleen and at lower levels in other tissues associated with endocrine and immunologic/hematologic functions. It is thought to be a receptor for N arachidonyl glycine. It may contribute to regulation of the immune system.

Pathway

Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Signal Transduction, organism-specific biosystem.