Rabbit Anti-Human GPR179 (a.a. 26-381) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human GPR179 protein; Source: E. coli derived, PET28a; Tag: 6*His; Domain: 26-381 aa of NM_001004334.3

Conjugate

Application Notes

WB: 1:1000-1:6000
IHC: 1:250-1:1000

General Notes

This product (Catalog No. DPABH-18590) is a rabbit-derived polyclonal antibody raised against human GPR179, targeting the amino acid region 26–381 of the protein. This antibody exhibits cross-reactivity with Human GPR179 from mouse. It has been affinity purified by Protein A. GPR179 (Probable G-protein coupled receptor 179) belongs to the glutamate receptor subfamily of GPCRs, which is involved in signal transduction through retinal depolarizing bipolar cells. The protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. GPR179 is expressed in retinal bipolar cells and upregulated in rd1 mice retina with Pde6b mutations (PubMed: 22325361, PubMed: 22325362).
DPABH-18590 is suitable for use in Western blot (WB) (1:1,000–1:6,000), IHC (1:250–1:1,000) applications.
DPABH-18590 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

GPR158L1; G protein coupled receptor 179

Entrez Gene ID

UniProt ID