Mouse myeloma cell line NS0-derived recombinant human Osteoactivinisoform b. Lys23-Asn486 Accession Number NP_002501
Conjugate
Unconjugated
Applications
Application Notes
Western Blot 0.1 μg/mL; Immunohistochemistry 5-15 μg/mL; ELISA Capture 0.2-0.8 μg/mL; ELISA Detection 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DPABY-279 - DPABY-518
Osteoactivin, also known as transmembrane glycoprotein NMB (GPNMB) and dendritic cell-associated transmembrane protein (DC-HIL), is a type I transmembrane glycoprotein that is found either on the plasma membrane or on membranes of the endosome/lysosome compartment. The extracellular region of Osteoactivin contains a heparin-binding motif and an integrin recognition RGD domain, while the cytocylasmic region contains an immunoreceptor tyrosine-based activation motif (ITAM) and lysosomal targeting motif.
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