Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Pathway
Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling; Signal Transduction;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Poole, DP; Godfrey, C; et al. Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system. NEUROGASTROENTEROLOGY AND MOTILITY 22:-(2010).
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COA
Certificate of Analysis
