Specifications
Immunogen
A synthetic peptide of human GORASP1 is used for rabbit immunization.
Target
Alternative Names
GORASP1; golgi reassembly stacking protein 1, 65kDa; golgi phosphoprotein 5 , GOLPH5; Golgi reassembly-stacking protein 1; FLJ23443; GRASP65; P65; Golgi phosphoprotein 5; Golgi peripheral membrane protein p65; Golgi reassembly and stacking protein 1; golg
Product Background
Antigen Description
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined.
Pathway
Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; Golgi Cisternae Pericentriolar Stack Reorganization, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem; Mitotic Prophase, organism-specific biosystem;
Citations
Publication ()
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