Synthetic peptide within Human GLCNE aa 168-197 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q9Y223
Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.
Pathway
Amino sugar and nucleotide sugar metabolism; Asparagine N-linked glycosylation; Metabolism of proteins; Sialic acid metabolism
Citations
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