Specifications
Immunogen
GNB5 (NP_057278, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. The sequence is MCDQTFLVNVFGSCDKCFKQRALRPVFKKSQQLSYCSTCAEIMATEGLHENETLASLKSE AESLKGKLEEERAKLHDVELHQVAERVEAL
Target
Alternative Names
GNB5; guanine nucleotide binding protein (G protein), beta 5; GB5; guanine nucleotide-binding protein subunit beta-5; gbeta5; transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; guanine nucleotide-binding protein, beta subunit
Product Background
Antigen Description
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist.
Pathway
ADP signalling through P2Y purinoceptor 1; Activation of Kainate Receptors upon glutamate binding; Alcoholism; Aquaporin-mediated transport
Citations
Publication ()
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