Anti-GNB2 (full length) polyclonal antibody

Species Reactivity

Human

Immunogen

GNB2 (AAH10073, 1 a.a. ~ 340 a.a) full-length recombinant protein with GST tag. The sequence is MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYA MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNI CSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGF AGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYA FTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAM KGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN

Conjugate

Alternative Names

GNB2; guanine nucleotide binding protein (G protein), beta polypeptide 2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; transducin beta chain 2; g protein subunit beta-2; G protein, beta-2 subunit; guanine nucleotide-binding protein G(

Entrez Gene ID

UniProt ID

Antigen Description

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5 UTR.

Pathway

ADP signalling through P2Y purinoceptor 1; Activation of G protein gated Potassium channels; Activation of Kainate Receptors upon glutamate binding; Alcoholism.