Recombinant full length protein corresponding to Human GMPPA aa 1-420.Sequence: MLKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGM QEILLIGFYQPDEPLTQFLEAAQQEFNLPVRYLQEFAPLGTGGGLYHFRD QILAGSPEAFFVLNADVCSDFPLSAMLEAHRRQRHPFLLLGTTANRTQSL NYGCIVENPQTHEVLHYVEKPS
GMPPA (GDP-mannose pyrophosphorylase A) is a protein-coding gene. Diseases associated with GMPPA include tuberculosis, and among its related super-pathways are GDP-mannose biosynthesis and WNT ligand biogenesis and trafficking. GO annotations related to this gene include mannose-1-phosphate guanylyltransferase activity and GTP binding. An important paralog of this gene is GMPPB.
Pathway
Amino sugar and nucleotide sugar metabolism; Asparagine N-linked glycosylation; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein; Fructose and mannose metabolism; GDP-mannose biosynthesi
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