A synthetic peptide corresponding to residues in Human GLYR1 was used as an immunogen, Q49A26. (The amino acid sequence is considered to be commercially sensitive.)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100;
Target
Alternative Names
GLYR1; glyoxylate reductase 1 homolog (Arabidopsis); putative oxidoreductase GLYR1; BM045; HIBDL; N PAC; NP60; nuclear protein 60kDa; nuclear protein NP60; nuclear protein 60 kDa; nuclear protein of 60 kDa; cytokine-like nuclear factor n-pac; 3-hydroxyiso
May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated Lys-36 of histone H3 (H3K36me3).
Citations
Publication ()
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