Recombinant fragment corresponding to Human GLTPD1 aa 1-28 (N terminal).Sequence: MDDSETGFNLKVVLVSFKQCLDEKEEVL Database link: Q5TA50
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/20 - 1/50;
Target
Alternative Names
GLTPD1; glycolipid transfer protein domain containing 1; CPTP; ceramide-1-phosphate transfer protein; GLTP domain-containing protein 1; glycolipid transfer protein domain-containing protein 1;
Mediates the intracellular transfer of ceramide-1-phosphate between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. Has no activity with galactosylceramide, lactosylceramide, sphingomyelin, phosphatidylcholine, phosphatidic acid and ceramide.
Citations
Publication ()
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