Specifications
Immunogen
A synthetic peptide of human GINS2 is used for rabbit immunization.
Target
Alternative Names
GINS2; GINS complex subunit 2 (Psf2 homolog); DNA replication complex GINS protein PSF2; Pfs2; PSF2; HSPC037;
Product Background
Antigen Description
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.
Pathway
Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; DNA strand elongation, organism-specific biosystem; GINS complex, organism-specific biosystem; S Phase, organism-specific biosystem; Synthesis of DNA, organism-specific biosystem.
Citations
Publication ()
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COA
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