Specifications
Immunogen
a 17 amino acid peptide near the carboxy-terminus of the human GDF6.
Target
Alternative Names
GDF6; growth differentiation factor 6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; LCA17; MCOP4; SCDO4; BMP-13; MCOPCB6; growth/differentiation factor 6; GDF-6; Klippel-Feil syndrome; Klip-Feil malformation; Klippel-Feil malformation; bone morphogenetic pro
Product Background
Antigen Description
This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation. [provided by RefSeq, Jul 2008]
Pathway
Hippo signaling pathway; TGF-beta signaling pathway
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Mumm, JB; Ekmekcioglu, S; et al. Soluble human MDA-7/IL-24: Characterization of the molecular form(s) inhibiting tumor growth and stimulating monocytes. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 26:877-886(2006).
Shen, YC; Wang, JF; et al. Effectors of Epidermal Growth Factor Receptor Pathway: The Genetic Profiling of KRAS, BRAF, PIK3CA, NRAS Mutations in Colorectal Cancer Characteristics and Personalized Medicine. PLOS ONE 8:-(2013).
COA
Certificate of Analysis
