Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human GCDH aa 1-100. The exact sequence is proprietary.Database link: Q92947
Applications
Application Notes
WB: 1/1000 - 1/10000; Flow Cyt: 1/80.
Target
Alternative Names
GCDH; glutaryl-CoA dehydrogenase; glutaryl Coenzyme A dehydrogenase; glutaryl-CoA dehydrogenase, mitochondrial; ACAD5; glutaryl-Coenzyme A dehydrogenase; GCD;
Product Background
Antigen Description
Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive.
Pathway
Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Lysine catabolism, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Lysine degradation, lysine =>
Citations
Publication ()
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COA
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