Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis.
Pathway
Arginine and proline metabolism; Creatine metabolism; Creatine pathway; Glycine, serine and threonine metabolism;
Citations
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