Full length protein corresponding to Human GAS2 aa 1-313. (NP_005247.1).Sequence: MCTALSPKVRSGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLGK EITAETFMEKLDNGALLCQLAETMQEKFKESMDANKPTKNLPLKKIPCKT SAPSGSFFARDNTANFLSWCRDLGVDETCLFESEGLVLHKQPREVCLCLL ELGRIAARYGVEPPGLIKLE
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
GAS2; growth arrest-specific 2; growth arrest-specific protein 2; GAS-2; MGC32610;
May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process.
Pathway
Apoptosis; Apoptotic cleavage of cellular proteins; Apoptotic executionphase; Caspase cascade in apoptosis; Caspase-mediated cleavage of cytoskeletal proteins;
Citations
Publication ()
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