This product (Catalog No. DPABH-22550) is a rabbit-derived polyclonal antibody raised against human GANC. This antibody exhibits cross-reactivity with GANC from mouse. It has been affinity purified by Protein A. Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. DPABH-22550 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:300) applications. DPABH-22550 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
GANC; glucosidase, alpha; neutral C; neutral alpha-glucosidase C
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