Specifications
Immunogen
A synthetic peptide of human GAL3ST1 is used for rabbit immunization.
Target
Alternative Names
GAL3ST1; galactose-3-O-sulfotransferase 1; galactosylceramide sulfotransferase; cerebroside (3 phosphoadenylylsulfate:galactosylceramide 3) sulfotransferase; CST; GalCer sulfotransferase; cerebroside sulfotransferase; 3-phosphoadenosine-5-phosphosulfate:G
Product Background
Antigen Description
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3-phosphoadenylylsulfate + a galactosylceramide to adenosine 3,5-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.
Pathway
Cerebroside and sulfatide biosynthesis, organism-specific biosystem; Cerebroside and sulfatide biosynthesis, conserved biosystem; Glycosphingolipid metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem;
Citations
Publication ()
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