Rabbit Anti-Human GABPB2 (a.a. 129-220) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human GABPB2 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 129-220 aa of BC027033

Conjugate

Application Notes

WB: 1:500-1:1000

General Notes

This product (Catalog No. DPABH-28801) is a rabbit-derived polyclonal antibody raised against human GABPB2, targeting the amino acid region 129–220 of the protein. This antibody exhibits cross-reactivity with Human GABPB2 from mouse and rat. It has been affinity purified by Protein A. GABPB2 is a subunit of the GA-binding protein (GABP) transcription factor, which is a heterodimeric complex. The GABP complex plays a role in the regulation of gene transcription by binding to specific DNA sequences. GABPB2 specifically contributes to the transactivation of target genes. The protein is primarily located in the nucleus. It is ubiquitously expressed in various tissues, including testis, ovary, and others. Studies have shown that GABPB2 is dispensable for normal lymphocyte development but moderately affects B cell responses (PMID: 18628204). Mice deficient in GABPB2 exhibit increased B cell proliferation and antibody production in response to certain stimuli. The molecular weight of GABPB2 is 48 kDa.
DPABH-28801 is suitable for use in Western blot (WB) (1:500–1:1,000) application.
DPABH-28801 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

GABPB-2; GABPB 2; GABP subunit beta-2; GABP subunit beta 2; GA-binding protein subunit beta-2

Entrez Gene ID

UniProt ID