A synthetic peptide of human GAB3 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
GAB3; GRB2-associated binding protein 3; GRB2-associated-binding protein 3; DOS/Gab family member 3; GRB2-associated binder 3; Gab3 scaffolding protein; growth factor receptor bound protein 2-associated protein 3;
This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants.
Citations
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