Anti-G Protein monoclonal antibody (DMABT-H21660)

Mouse anti-Bovine G Protein monoclonal antibody for WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2D
Species Reactivity
Bovine
Immunogen
Bovine brain Goalpha purified by the method of Sternweis and Robishaw (J. Biol. Chem. [1984] 259, 13806).
Conjugate
Unconjugated

Applications


Application Notes
Western blot 1:1000. Labels a single protein band of 39-42 kDa in bovine and rat membranes.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
G protein, G alpha i-1; G protein, G alpha i-1 PAb; Anti-G protein, G alpha i-1 PAb; Rabbit Anti-G protein, G alpha i-1 PAb; G protein, G alpha i-1 Polyclonal Antibody; G protein, G alpha i-1 Antibody

Product Background


Antigen Description
The G protein family of signal transducers includes6heterotrimers, which are most clearly distinguished by their different alpha chains; they have virtually identical beta chains and similar gamma chains. G protein alpha inhibitor chain 2 is a subunit of the G(i) G protein, whose role is in inhibiting adenylate cyclase activity in response to bound GTP. The G proteins possess GTPase activity and are components of a complex membrane signaling system that includes membrane bound receptors. The system exists to modulate extracellular signals as they are transmitted into the cell.

Citations


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References


Correia, M; Thiagarajan, V; et al. Modulating the Structure of EGFR with UV Light: New Possibilities in Cancer Therapy. PLOS ONE 9:-(2014).
Wandtke, T; Wozniak, J; et al. Aptamers in Diagnostics and Treatment of Viral Infections. VIRUSES-BASEL 7:751-780(2015).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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