FZD3 (NP_059108, 55 a.a. ~ 157 a.a) partial recombinant protein with GST tag. The sequence is QQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLM EMFGVPWPEDMECSRFPDCDEPYPRLVDLNLAGEPTEGAPVAV
Conjugate
Unconjugated
Target
Alternative Names
FZD3; frizzled class receptor 3; Fz-3; frizzled-3; frizzled homolog 3; frizzled family receptor 3; frizzled 3, seven transmembrane spanning receptor;
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.
Pathway
Asymmetric localization of PCP proteins; Basal cell carcinoma; Class B/2 (Secretin family receptors); HTLV-I infection
Citations
Publication ()
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