Mouse myeloma cell line NS0-derived recombinant human sFRP-3. Ala33-Asn325 Accession Number AAB51298
Conjugate
Unconjugated
Applications
Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.5-2.0 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-4138 - DCABY-4306
Secreted Frizzled related proteins are secreted glycoproteins with homology to the Wnt-binding domain of the Frizzled family of transmembrane receptors. sFRPs contain an N-terminal Frizzled-like cysteine-rich domain (CRD) with 10 conserved cysteines and a C-terminal heparin-binding region. sFRPs function as soluble antagonists of Wnt signaling by binding directly to Wnt proteins and preventing their interactions with Frizzled receptors.
Pathway
Adipogenesis; Endochondral Ossification;
Citations
Publication ()
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