Anti-FRAT2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human FRAT2 is used for rabbit immunization.

Conjugate

Alternative Names

FRAT2; frequently rearranged in advanced T-cell lymphomas 2; GSK-3-binding protein FRAT2; GSK 3 binding protein FRAT2; FRAT-2; GSK-3 binding protein FRAT2; MGC10562;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.

Pathway

Beta-catenin phosphorylation cascade, organism-specific biosystem; Degradation of beta-catenin by the destruction complex, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Wnt, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem;