Full length protein corresponding to Human FOXH1 aa 1-365. (AAI11605.1).Sequence: MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLAMIALVIQAAP SRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAK PQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAFAKDLGPYVLH GRPYRPPSPPPPPSEGFSIK
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
FOXH1; forkhead box H1; forkhead box protein H1; FAST1; fast-2; hFAST-1; TGF-beta/activin signal transducer; forkhead activin signal transducer 2; forkhead activin signal transducer-1; FAST-1;
Transcriptional activator. Recognizes and binds to the DNA sequence 5-TGT[GT][GT]ATT-3. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Pathway
Developmental Biology; Heart Development; Regulation of nuclear SMAD2/3 signaling; Signaling by NODAL; TGF Beta Signaling Pathway; TGF-beta Receptor Signaling Pathway;
Citations
Publication ()
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COA
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