FOXA1 (NP_004487, 367 a.a. ~ 472 a.a) partial recombinant protein with GST tag. The sequence is LASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQALQY SPYGSTLPASLPLGSASVTTRSPIEPSALEPAYYQGVYSRPVLNTS
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.
Pathway
Direct p53 effectors; FOXA1 transcription factor network; Prostate Cancer;
Citations
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