Anti-FOSB monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human FOSB is used for rabbit immunization.

Conjugate

Alternative Names

FOSB; FBJ murine osteosarcoma viral oncogene homolog B; protein fosB; activator protein 1; AP 1; DKFZp686C0818; GOS3; GOSB; G0S3; MGC42291; oncogene FOS B; G0/G1 switch regulatory protein 3; AP-1;

Entrez Gene ID

UniProt ID

Antigen Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Pathway

Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Cocaine addiction, organism-specific biosystem; Cocaine addiction, conserved biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;