Anti-FLT4 monoclonal antibody (DCABY-4255)

Rat Anti-Mouse FLT4 monoclonal antibody for ELISA(Cap) Datasheet

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Specifications


Host Species
Rat
Antibody Isotype
IgG2a
Clone
203905
Species Reactivity
Mouse
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse VEGFR3/Flt-4. Tyr25-Asp770 Accession Number Q5SU94
Conjugate
Unconjugated

Applications


Application Notes
ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4255 - DPABY-586
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
FLT4; FMS-like tyrosine kinase 4; Chy; Flt-4; VEGFR3; VEGFR-3
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytokine-cytokine receptor interaction; Focal adhesion; PI3K-Akt signaling pathway; Rap1 signaling pathway; Ras signaling pathway; Signal Transduction; Signaling by VEGF; VEGF binds to VEGFR leading to receptor dimerization;

Citations


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References


Weich, HA; Bando, H; et al. Quantification of vascular endothelial growth factor-C (VEGF-C) by a novel ELISA. JOURNAL OF IMMUNOLOGICAL METHODS 285:145-155(2004).
Achen, MG; Roufail, S; et al. Monoclonal antibodies to vascular endothelial growth factor-D block its interactions with both VEGF receptor-2 and VEGF receptor-3. EUROPEAN JOURNAL OF BIOCHEMISTRY 267:2505-2515(2000).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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