Anti-FKBP6 monoclonal antibody, clone 9G20

Antibody Isotype

IgG2a

Clone

9G20

Species Reactivity

Human

Immunogen

FKBP6 (NP_003593.2, 1 a.a. ~ 108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

FKBP6; FK506 binding protein 6, 36kDa; FK506 binding protein 6 (36kD); peptidyl-prolyl cis-trans isomerase FKBP6; FKBP36; immunophilin FKBP36; peptidylprolyl cis trans isomerase; PPIase; rotamase; FKBP-36; 36 kDa FKBP; PPIase FKBP6; FK506-binding protein

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein may have cis-trans prolyl isomerase activity, and binds to clathrin heavy chain and heat shock protein 72. This gene is found to be deleted in Williams syndrome, and the orthologous gene in mouse is essential for fertility and homologous pairing in male meiosis.

Pathway

Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Meiosis, organism-specific biosystem; Meiotic Synapsis, organism-specific biosystem;